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pH sensing via bicarbonate-regulated “soluble” adenylyl cyclase (sAC)
Soluble adenylyl cyclase (sAC) is a source of the second messenger cyclic adenosine 3′, 5′ monophosphate (cAMP). sAC is directly regulated by bicarbonate (HCO(−)(3)) ions. In living cells, HCO(−)(3) ions are in nearly instantaneous equilibrium with carbon dioxide (CO(2)) and pH due to the ubiquitous...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838963/ https://www.ncbi.nlm.nih.gov/pubmed/24324443 http://dx.doi.org/10.3389/fphys.2013.00343 |