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Dendritic Cell Plasticity in Tumor-Conditioned Skin: CD14(+) Cells at the Cross-Roads of Immune Activation and Suppression

Tumors abuse myeloid plasticity to re-direct dendritic cell (DC) differentiation from T cell stimulatory subsets to immune-suppressive subsets that can interfere with anti-tumor immunity. Lined by a dense network of easily accessible DC the skin is a preferred site for the delivery of DC-targeted va...

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Detalles Bibliográficos
Autores principales: van de Ven, Rieneke, Lindenberg, Jelle J., Oosterhoff, Dinja, de Gruijl, Tanja D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839226/
https://www.ncbi.nlm.nih.gov/pubmed/24324467
http://dx.doi.org/10.3389/fimmu.2013.00403