Diagnostic Application of hMLH1 Methylation in Hereditary Non-Polyposis Colorectal Cancer

Colorectal cancer (CRC) due to mismatch repair (MMR) defect has distinct characteristics among unselected CRCs. These CRCs are biologically less aggressive and, thus, showing better prognosis but less sensitive to the 5FU-based chemotherapy. CRCs with MMR defect derive from both hereditary and spora...

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Detalles Bibliográficos
Autor principal: Matsubara, Nagahide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2004
Materias:
Other
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839271/
https://www.ncbi.nlm.nih.gov/pubmed/15528793
http://dx.doi.org/10.1155/2004/371941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839271/
https://www.ncbi.nlm.nih.gov/pubmed/15528793
http://dx.doi.org/10.1155/2004/371941

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