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Massive endocytosis triggered by surface membrane palmitoylation under mitochondrial control in BHK fibroblasts

Large Ca transients cause massive endocytosis (MEND) in BHK fibroblasts by nonclassical mechanisms. We present evidence that MEND depends on mitochondrial permeability transition pore (PTP) openings, followed by coenzyme A (CoA) release, acyl CoA synthesis, and membrane protein palmitoylation. MEND...

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Detalles Bibliográficos
Autores principales: Hilgemann, Donald W, Fine, Michael, Linder, Maurine E, Jennings, Benjamin C, Lin, Mei-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839538/
https://www.ncbi.nlm.nih.gov/pubmed/24282236
http://dx.doi.org/10.7554/eLife.01293