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Autophagy is Impaired in the Tibialis Anterior of Dystrophin Null Mice

Background Duchenne muscular dystrophy is a lethal, progressive, muscle-wasting disease caused by mutations in the DMD gene. Structural remodelling processes are responsible for muscle atrophy and replacement of myofibers by fibrotic and adipose tissues. Molecular interventions modulating catabolic...

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Detalles Bibliográficos
Autores principales: Spitali, Pietro, Grumati, Paolo, Hiller, Monika, Chrisam, Martina, Aartsma-Rus, Annemieke, Bonaldo, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839594/
https://www.ncbi.nlm.nih.gov/pubmed/24292657
http://dx.doi.org/10.1371/currents.md.e1226cefa851a2f079bbc406c0a21e80