Завантаження...
Multidrug resistance in chronic myeloid leukaemia: how much can we learn from MDR–CML cell lines?
The hallmark of CML (chronic myeloid leukaemia) is the BCR (breakpoint cluster region)–ABL fusion gene. CML evolves through three phases, based on both clinical and pathological features: a chronic phase, an accelerated phase and blast crisis. TKI (tyrosine kinase inhibitors) are the treatment modal...
Автори: | , , |
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Формат: | Online Стаття Текст |
Мова: | English |
Опубліковано: |
Portland Press Ltd.
2013
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Предмети: | |
Онлайн доступ: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839595/ https://www.ncbi.nlm.nih.gov/pubmed/24070327 http://dx.doi.org/10.1042/BSR20130067 |