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Multidrug resistance in chronic myeloid leukaemia: how much can we learn from MDR–CML cell lines?

The hallmark of CML (chronic myeloid leukaemia) is the BCR (breakpoint cluster region)–ABL fusion gene. CML evolves through three phases, based on both clinical and pathological features: a chronic phase, an accelerated phase and blast crisis. TKI (tyrosine kinase inhibitors) are the treatment modal...

Повний опис

Бібліографічні деталі
Автори: Rumjanek, Vivian M., Vidal, Raphael S., Maia, Raquel C.
Формат: Online Стаття Текст
Мова:English
Опубліковано: Portland Press Ltd. 2013
Предмети:
Онлайн доступ:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839595/
https://www.ncbi.nlm.nih.gov/pubmed/24070327
http://dx.doi.org/10.1042/BSR20130067