Multidrug resistance in chronic myeloid leukaemia: how much can we learn from MDR–CML cell lines?

The hallmark of CML (chronic myeloid leukaemia) is the BCR (breakpoint cluster region)–ABL fusion gene. CML evolves through three phases, based on both clinical and pathological features: a chronic phase, an accelerated phase and blast crisis. TKI (tyrosine kinase inhibitors) are the treatment modal...

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Detalles Bibliográficos
Autores principales: Rumjanek, Vivian M., Vidal, Raphael S., Maia, Raquel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839595/
https://www.ncbi.nlm.nih.gov/pubmed/24070327
http://dx.doi.org/10.1042/BSR20130067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839595/
https://www.ncbi.nlm.nih.gov/pubmed/24070327
http://dx.doi.org/10.1042/BSR20130067

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