PRC2 binds to active promoters and contacts nascent RNAs in embryonic stem cells

EZH2 is the catalytic subunit of PRC2, a central epigenetic repressor essential for development processes in vivo and for the differentiation of embryonic stem cells (ESCs) in vitro. The biochemical function of PRC2 in depositing repressive H3K27me3 marks is well understood, but how it is regulated...

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Detalles Bibliográficos
Autores principales: Kaneko, Syuzo, Son, Jinsook, Shen, Steven S., Reinberg, Danny, Bonasio, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839660/
https://www.ncbi.nlm.nih.gov/pubmed/24141703
http://dx.doi.org/10.1038/nsmb.2700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839660/
https://www.ncbi.nlm.nih.gov/pubmed/24141703
http://dx.doi.org/10.1038/nsmb.2700

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