Targeted delivery of let-7a microRNA encapsulated ephrin-A1 conjugated liposomal nanoparticles inhibit tumor growth in lung cancer

MicroRNAs (miRs) are small noncoding RNA sequences that negatively regulate the expression of target genes by posttranscriptional repression. miRs are dysregulated in various diseases, including cancer. let-7a miR, an antioncogenic miR, is downregulated in lung cancers. Our earlier studies demonstra...

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Detalles Bibliográficos
Autores principales: Lee, Hung-Yen, Mohammed, Kamal A, Kaye, Fredric, Sharma, Parvesh, Moudgil, Brij M, Clapp, William L, Nasreen, Najmunnisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839802/
https://www.ncbi.nlm.nih.gov/pubmed/24293999
http://dx.doi.org/10.2147/IJN.S41782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839802/
https://www.ncbi.nlm.nih.gov/pubmed/24293999
http://dx.doi.org/10.2147/IJN.S41782

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