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Targeted delivery of let-7a microRNA encapsulated ephrin-A1 conjugated liposomal nanoparticles inhibit tumor growth in lung cancer
MicroRNAs (miRs) are small noncoding RNA sequences that negatively regulate the expression of target genes by posttranscriptional repression. miRs are dysregulated in various diseases, including cancer. let-7a miR, an antioncogenic miR, is downregulated in lung cancers. Our earlier studies demonstra...
Autores principales: | Lee, Hung-Yen, Mohammed, Kamal A, Kaye, Fredric, Sharma, Parvesh, Moudgil, Brij M, Clapp, William L, Nasreen, Najmunnisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839802/ https://www.ncbi.nlm.nih.gov/pubmed/24293999 http://dx.doi.org/10.2147/IJN.S41782 |
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