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Gain of Function Notch Phenotypes Associated with Ectopic Expression of the Su(H) C-Terminal Domain Illustrate Separability of Notch and Hairless-Mediated Activities

The Notch signaling pathway is instrumental for cell fate decisions. Signals from the Notch receptor are transduced by CSL-type DNA-binding proteins. In Drosophila, this protein is named Suppressor of Hairless [Su(H)]. Together with the intracellular domain of the activated Notch receptor ICN, Su(H)...

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Detalles Bibliográficos
Autores principales: Maier, Dieter, Praxenthaler, Heiko, Schulz, Adriana, Preiss, Anette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839874/
https://www.ncbi.nlm.nih.gov/pubmed/24282610
http://dx.doi.org/10.1371/journal.pone.0081578