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Gain of Function Notch Phenotypes Associated with Ectopic Expression of the Su(H) C-Terminal Domain Illustrate Separability of Notch and Hairless-Mediated Activities
The Notch signaling pathway is instrumental for cell fate decisions. Signals from the Notch receptor are transduced by CSL-type DNA-binding proteins. In Drosophila, this protein is named Suppressor of Hairless [Su(H)]. Together with the intracellular domain of the activated Notch receptor ICN, Su(H)...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839874/ https://www.ncbi.nlm.nih.gov/pubmed/24282610 http://dx.doi.org/10.1371/journal.pone.0081578 |