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Insulin/IGF-I Signaling Pathways Enhances Tumor Cell Invasion through Bisecting GlcNAc N-glycans Modulation. An Interplay with E-Cadherin

Changes in glycosylation are considered a hallmark of cancer, and one of the key targets of glycosylation modifications is E-cadherin. We and others have previously demonstrated that E-cadherin has a role in the regulation of bisecting GlcNAc N-glycans expression, remaining to be determined the E-ca...

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Detalles Bibliográficos
Autores principales: de-Freitas-Junior, Julio Cesar Madureira, Carvalho, Sandra, Dias, Ana M., Oliveira, Patrícia, Cabral, Joana, Seruca, Raquel, Oliveira, Carla, Morgado-Díaz, José Andrés, Reis, Celso A., Pinho, Salomé S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839884/
https://www.ncbi.nlm.nih.gov/pubmed/24282611
http://dx.doi.org/10.1371/journal.pone.0081579