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Mycobacterial Phosphatidylinositol Mannoside 6 (PIM(6)) Up-Regulates TCR-Triggered HIV-1 Replication in CD4(+) T Cells

Tuberculosis (TB) is the leading cause of mortality among those infected with human immunodeficiency virus (HIV-1) worldwide. HIV-1 load and heterogeneity are increased both locally and systemically in active TB. Mycobacterium tuberculosis (MTB) infection supports HIV-1 replication through dysregula...

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Detalles Bibliográficos
Autores principales: Rodriguez, Myriam E., Loyd, Candace M., Ding, Xuedong, Karim, Ahmad F., McDonald, David J., Canaday, David H., Rojas, Roxana E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839890/
https://www.ncbi.nlm.nih.gov/pubmed/24282561
http://dx.doi.org/10.1371/journal.pone.0080938