The Origin of the RB1 Imprint

The human RB1 gene is imprinted due to a differentially methylated CpG island in intron 2. This CpG island is part of PPP1R26P1, a truncated retrocopy of PPP1R26, and serves as a promoter for an alternative RB1 transcript. We show here by in silico analyses that the parental PPP1R26 gene is present...

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Detalles Bibliográficos
Autores principales: Kanber, Deniz, Buiting, Karin, Roos, Christian, Gromoll, Jörg, Kaya, Sabine, Horsthemke, Bernhard, Lohmann, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839921/
https://www.ncbi.nlm.nih.gov/pubmed/24282601
http://dx.doi.org/10.1371/journal.pone.0081502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839921/
https://www.ncbi.nlm.nih.gov/pubmed/24282601
http://dx.doi.org/10.1371/journal.pone.0081502

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