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Structural Analysis of microRNA-Target Interaction by Sequential Seed Mutagenesis and Stem-Loop 3' RACE

BACKGROUND: As a consequence of recent RNAseq efforts, miRNAomes of diverse tissues and species are available. However, most interactions between microRNAs and regulated mRNAs are still to be deciphered. While in silico analysis of microRNAs results in prediction of hundreds of potential targets, bo...

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Detalles Bibliográficos
Autores principales: Bohmer, Marc, Sharbati, Jutta, zur Bruegge, Jennifer, Einspanier, Ralf, Sharbati, Soroush
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839922/
https://www.ncbi.nlm.nih.gov/pubmed/24282594
http://dx.doi.org/10.1371/journal.pone.0081427