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Proteasome, but Not Autophagy, Disruption Results in Severe Eye and Wing Dysmorphia: A Subunit- and Regulator-Dependent Process in Drosophila

Proteasome-dependent and autophagy-mediated degradation of eukaryotic cellular proteins represent the two major proteostatic mechanisms that are critically implicated in a number of signaling pathways and cellular processes. Deregulation of functions engaged in protein elimination frequently leads t...

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Detalles Bibliográficos
Autores principales: Velentzas, Panagiotis D., Velentzas, Athanassios D., Pantazi, Asimina D., Mpakou, Vassiliki E., Zervas, Christos G., Papassideri, Issidora S., Stravopodis, Dimitrios J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839973/
https://www.ncbi.nlm.nih.gov/pubmed/24282550
http://dx.doi.org/10.1371/journal.pone.0080530