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Fetal Calcium Regulates Branching Morphogenesis in the Developing Human and Mouse Lung: Involvement of Voltage-Gated Calcium Channels

Airway branching morphogenesis in utero is essential for optimal postnatal lung function. In the fetus, branching morphogenesis occurs during the pseudoglandular stage (weeks 9–17 of human gestation, embryonic days (E)11.5–16.5 in mouse) in a hypercalcaemic environment (∼1.7 in the fetus vs. ∼1.1–1....

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Detalles Bibliográficos
Autores principales: Brennan, Sarah C., Finney, Brenda A., Lazarou, Maria, Rosser, Anne E., Scherf, Caroline, Adriaensen, Dirk, Kemp, Paul J., Riccardi, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840017/
https://www.ncbi.nlm.nih.gov/pubmed/24282533
http://dx.doi.org/10.1371/journal.pone.0080294