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DNA-PK Target Identification Reveals Novel Links between DNA Repair Signaling and Cytoskeletal Regulation

The DNA-dependent protein kinase (DNA-PK) may function as a key signaling kinase in various cellular pathways other than DNA repair. Using a two-dimensional gel electrophoresis approach and stable DNA double-strand break-mimicking molecules (Dbait32Hc) to activate DNA-PK in the nucleus and cytoplasm...

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Detalles Bibliográficos
Autores principales: Kotula, Ewa, Faigle, Wolfgang, Berthault, Nathalie, Dingli, Florent, Loew, Damarys, Sun, Jian-Sheng, Dutreix, Marie, Quanz, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840018/
https://www.ncbi.nlm.nih.gov/pubmed/24282534
http://dx.doi.org/10.1371/journal.pone.0080313