Analytic Review of Modeling Studies of ARV Based PrEP Interventions Reveals Strong Influence of Drug-Resistance Assumptions on the Population-Level Effectiveness

BACKGROUND: Four clinical trials have shown that oral and topical pre-exposure prophylaxis (PrEP) based on tenofovir may be effective in preventing HIV transmission. The expected reduction in HIV transmission and the projected prevalence of drug resistance due to PrEP use vary significantly across m...

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Detalles Bibliográficos
Autores principales: Dimitrov, Dobromir, Boily, Marie-Claude, Brown, Elizabeth R., Hallett, Timothy B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840039/
https://www.ncbi.nlm.nih.gov/pubmed/24282559
http://dx.doi.org/10.1371/journal.pone.0080927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840039/
https://www.ncbi.nlm.nih.gov/pubmed/24282559
http://dx.doi.org/10.1371/journal.pone.0080927

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