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Knockdown of Selenocysteine-Specific Elongation Factor in Amblyomma maculatum Alters the Pathogen Burden of Rickettsia parkeri with Epigenetic Control by the Sin3 Histone Deacetylase Corepressor Complex

Selenocysteine is the 21st naturally-occurring amino acid. Selenoproteins have diverse functions and many remain uncharacterized, but they are typically associated with antioxidant activity. The incorporation of selenocysteine into the nascent polypeptide chain recodes the TGA stop codon and this pr...

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Detalles Bibliográficos
Autores principales: Adamson, Steven W., Browning, Rebecca E., Budachetri, Khemraj, Ribeiro, José M. C., Karim, Shahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840058/
https://www.ncbi.nlm.nih.gov/pubmed/24282621
http://dx.doi.org/10.1371/journal.pone.0082012