Mechanism of suppression of sustained neuronal spiking under high-frequency stimulation

Using Hodgkin–Huxley and isolated subthalamic nucleus (STN) model neurons as examples, we show that electrical high-frequency stimulation (HFS) suppresses sustained neuronal spiking. The mechanism of suppression is explained on the basis of averaged equations derived from the original neuron equatio...

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Detalles Bibliográficos
Autores principales: Pyragas, Kestutis, Novičenko, Viktor, Tass, Peter Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840296/
https://www.ncbi.nlm.nih.gov/pubmed/24146294
http://dx.doi.org/10.1007/s00422-013-0567-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840296/
https://www.ncbi.nlm.nih.gov/pubmed/24146294
http://dx.doi.org/10.1007/s00422-013-0567-1

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