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MMP-independent role of TIMP-1 at the blood brain barrier during viral encephalomyelitis

Infection of the CNS (central nervous system) with a sublethal neurotropic coronavirus (JHMV) induces a vigorous inflammatory response. CD4(+) and CD8(+) T cells are essential to control infectious virus but at the cost of tissue damage. An enigma in understanding the contribution of T cell subsets...

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Detalles Bibliográficos
Autores principales: Savarin, Carine, Bergmann, Cornelia C., Hinton, David R., Stohlman, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840398/
https://www.ncbi.nlm.nih.gov/pubmed/24156369
http://dx.doi.org/10.1042/AN20130033