A multi-arm multi-stage clinical trial design for binary outcomes with application to tuberculosis

BACKGROUND: Randomised controlled trials are becoming increasingly costly and time-consuming. In 2011, Royston and colleagues proposed a particular class of multi-arm multi-stage (MAMS) designs intended to speed up the evaluation of new treatments in phase II and III clinical trials. Their design, w...

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Detalles Bibliográficos
Autores principales: Bratton, Daniel J, Phillips, Patrick PJ, Parmar, Mahesh KB
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840569/
https://www.ncbi.nlm.nih.gov/pubmed/24229079
http://dx.doi.org/10.1186/1471-2288-13-139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840569/
https://www.ncbi.nlm.nih.gov/pubmed/24229079
http://dx.doi.org/10.1186/1471-2288-13-139

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