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Cytonemes are required for the establishment of a normal Hedgehog morphogen gradient in Drosophila epithelia
Hedgehog (Hh) signalling is important in development, stem cell biology and disease. In a variety of tissues, Hh acts as a morphogen to regulate growth and cell fate specification. Several hypotheses have been proposed to explain morphogen movement, one of which is transport via filopodia-like protr...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840581/ https://www.ncbi.nlm.nih.gov/pubmed/24121526 http://dx.doi.org/10.1038/ncb2856 |