Cargando…

Role of IGF-1 pathway in lung fibroblast activation

BACKGROUND: IGF-1 is elevated in pulmonary fibrosis and acute lung injury, where fibroblast activation is a prominent feature. We previously demonstrated that blockade of IGF pathway in murine model of lung fibrosis improved outcome and decreased fibrosis. We now expand that study to examine effects...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hung, Chi F, Rohani, Maryam G, Lee, Sung-soon, Chen, Peter, Schnapp, Lynn M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840605/ https://www.ncbi.nlm.nih.gov/pubmed/24103846 http://dx.doi.org/10.1186/1465-9921-14-102

Ejemplares similares

Role of integrin alpha8 in murine model of lung fibrosis
por: Hung, Chi F., et al.
Publicado: (2018)

uPARAP Function in Cutaneous Wound Repair
por: Rohani, Maryam G., et al.
Publicado: (2014)

Endotoxin-induced acute lung injury in mice with postnatal deletion of nephronectin
por: Wilson, Carole L., et al.
Publicado: (2022)

The role of IGF-pathway biomarkers in determining risks, screening, and prognosis in lung cancer
por: Pohlman, Alexander W., et al.
Publicado: (2022)

Octreotide inhibits secretion of IGF-1 from orbital fibroblasts in patients with thyroid-associated ophthalmopathy via inhibition of the NF-κB pathway
por: Kim, Sung Eun, et al.
Publicado: (2021)

Nuclear Targeting of IGF-1 Receptor in Orbital Fibroblasts from Graves' Disease: Apparent Role of ADAM17
por: Hoa, Neil, et al.
Publicado: (2012)

Effect of lung pericyte-like cell ablation on the bleomycin model of injury and repair
por: Hung, Chi F., et al.
Publicado: (2022)

Yak IGF2 Promotes Fibroblast Proliferation Via Suppression of IGF1R and PI3KCG Expression
por: Zhang, Quanwei, et al.
Publicado: (2018)

Pancreatic Fibroblasts Stimulate the Motility of Pancreatic Cancer Cells through IGF1/IGF1R Signaling under Hypoxia
por: Hirakawa, Toshiki, et al.
Publicado: (2016)

IGF-I induced genes in stromal fibroblasts predict the clinical outcome of breast and lung cancer patients
por: Rajski, Michal, et al.
Publicado: (2010)

Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway
por: Eliasz, Sandra, et al.
Publicado: (2010)

Alpha-Arbutin Promotes Wound Healing by Lowering ROS and Upregulating Insulin/IGF-1 Pathway in Human Dermal Fibroblast
por: Polouliakh, Natalia, et al.
Publicado: (2020)

TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1
por: Choi, Soo-Im, et al.
Publicado: (2014)

Widespread activation of immunity and pro‐inflammatory programs in peripheral blood leukocytes of HIV‐infected patients with impaired lung gas exchange
por: Crothers, Kristina, et al.
Publicado: (2016)

Antinematode Activity of Violacein and the Role of the Insulin/IGF-1 Pathway in Controlling Violacein Sensitivity in Caenorhabditis elegans
por: Ballestriero, Francesco, et al.
Publicado: (2014)

IGF/IGF-1R signal pathway in pain: a promising therapeutic target
por: Ma, Lulin, et al.
Publicado: (2023)

Corrigendum: Alpha-Arbutin Promotes Wound Healing by Lowering ROS and Upregulating Insulin/IGF-1 Pathway in Human Dermal Fibroblast
por: Polouliakh, Natalia, et al.
Publicado: (2021)

Novel role of cannabinoid receptor 2 in inhibiting EGF/EGFR and IGF-I/IGF-IR pathways in breast cancer
por: Elbaz, Mohamad, et al.
Publicado: (2016)

Insulin-Like Growth Factor (IGF) Pathway Targeting in Cancer: Role of the IGF Axis and Opportunities for Future Combination Studies
por: Simpson, Aaron, et al.
Publicado: (2017)

Serum insulin-like growth factor (IGF)-I and IGF-binding proteins in lung cancer patients.
por: Lee, D. Y., et al.
Publicado: (1999)

CXCL14 Maintains hESC Self-Renewal through Binding to IGF-1R and Activation of the IGF-1R Pathway
por: Cheng, Chih-Lun, et al.
Publicado: (2020)

The IGF-1 Signaling Pathway in Viral Infections
por: Józefiak, Agata, et al.
Publicado: (2021)

IGF-1 regulates the growth of fibroblasts and extracellular matrix deposition in pelvic organ prolapse
por: Yin, Yitong, et al.
Publicado: (2020)

Correction: Antinematode Activity of Violacein and the Role of the Insulin/IGF-1 Pathway in Controlling Violacein Sensitivity in Caenorhabditis elegans
por: Ballestriero, Francesco, et al.
Publicado: (2018)

Monocarboxylate transporter 4 promotes the migration of non‑cancerous L929 fibroblast cells by activating the IGF1/IGF1R/PIK3R3/SGK1 axis
por: Zhou, Xiaoju, et al.
Publicado: (2023)

Leptin stimulates IGF-1 transcription by activating AP-1 in human breast cancer cells
por: Min, Dong Yeong, et al.
Publicado: (2019)

Unique roles of Akt1 and Akt2 in IGF-IR mediated lung tumorigenesis
por: Franks, S. Elizabeth, et al.
Publicado: (2015)

Fetal intestinal fibroblasts respond to insulin-like growth factor (IGF)-II better than adult intestinal fibroblasts
por: Corkins, Mark R, et al.
Publicado: (2006)

Potential role of IGF-1/GLP-1 signaling activation in intracerebral hemorrhage
por: Siddiqui, Ehraz Mehmood, et al.
Publicado: (2022)

IGF-1R Inhibition Activates a YES/SFK Bypass Resistance Pathway: Rational Basis for Co-Targeting IGF-1R and Yes/SFK Kinase in Rhabdomyosarcoma()
por: Wan, Xiaolin, et al.
Publicado: (2015)

CD26 upregulates proliferation and invasion in keloid fibroblasts through an IGF-1-induced PI3K/AKT/mTOR pathway
por: Xin, Yu, et al.
Publicado: (2020)

Telomerase activity promotes osteoblast differentiation by modulating IGF-signaling pathway
por: Saeed, Hamid, et al.
Publicado: (2015)

A Single Second Shell Amino Acid Determines Affinity and Kinetics of Linagliptin Binding to Type 4 Dipeptidyl Peptidase and Fibroblast Activation Protein
por: Schnapp, Gisela, et al.
Publicado: (2020)

lncRNA NR2F1‐AS1 promotes breast cancer angiogenesis through activating IGF‐1/IGF‐1R/ERK pathway
por: Zhang, Qi, et al.
Publicado: (2020)

Role of pulmonary epithelial arginase‐II in activation of fibroblasts and lung inflammaging
por: Zhu, Cui, et al.
Publicado: (2023)

Activation of the IGF1R pathway potentially mediates acquired resistance to mutant-selective 3rd-generation EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer
por: Park, Ji Hyun, et al.
Publicado: (2016)

Role of IGF-1/IGF-1R in regulation of invasion in DU145 prostate cancer cells
por: Saikali, Zeina, et al.
Publicado: (2008)

IGF-1 mediated phosphorylation of specific IRS-1 serines in Ames dwarf fibroblasts is associated with longevity
por: Papaconstantinou, John, et al.
Publicado: (2015)

The Role of IGF-1 for Fracture Risk in Men
por: Vandenput, Liesbeth, et al.
Publicado: (2012)

Counteracting sarcopenia: the role of IGF-1 isoforms
por: Musarò, Antonio, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_29vnun5esslto55fvd7h60da37