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Increased sarcolemmal Na(+)/H(+) exchange activity in hypertrophied myocytes from dogs with chronic atrioventricular block

Dogs with compensated biventricular hypertrophy due to chronic atrioventricular block (cAVB), are more susceptible to develop drug-induced Torsade-de-Pointes arrhythmias and sudden cardiac death. It has been suggested that the increased Na(+) influx in hypertrophied cAVB ventricular myocytes contrib...

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Detalles Bibliográficos
Autores principales: van Borren, Marcel M. G. J., Vos, Marc A., Houtman, Marien J. C., Antoons, Gudrun, Ravesloot, Jan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840718/
https://www.ncbi.nlm.nih.gov/pubmed/24324438
http://dx.doi.org/10.3389/fphys.2013.00322