CSF-1R inhibition alters macrophage polarization and blocks glioma progression

Glioblastoma multiforme (GBM) comprises several molecular subtypes including proneural GBM. Most therapeutic approaches targeting glioma cells have failed. An alternative strategy is to target cells in the glioma microenvironment, such as tumor-associated macrophages and microglia (TAMs). Macrophage...

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Detalles Bibliográficos
Autores principales: Pyonteck, Stephanie M., Akkari, Leila, Schuhmacher, Alberto J., Bowman, Robert L., Sevenich, Lisa, Quail, Daniela F., Olson, Oakley C., Quick, Marsha L., Huse, Jason T., Teijeiro, Virginia, Setty, Manu, Leslie, Christina S., Oei, Yoko, Pedraza, Alicia, Zhang, Jianan, Brennan, Cameron W., Sutton, James C., Holland, Eric C., Daniel, Dylan, Joyce, Johanna A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840724/
https://www.ncbi.nlm.nih.gov/pubmed/24056773
http://dx.doi.org/10.1038/nm.3337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840724/
https://www.ncbi.nlm.nih.gov/pubmed/24056773
http://dx.doi.org/10.1038/nm.3337

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