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Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster

Ribosomes can read through stop codons in a regulated manner, elongating rather than terminating the nascent peptide. Stop codon readthrough is essential to diverse viruses, and phylogenetically predicted to occur in a few hundred genes in Drosophila melanogaster, but the importance of regulated rea...

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Detalles Bibliográficos
Autores principales: Dunn, Joshua G, Foo, Catherine K, Belletier, Nicolette G, Gavis, Elizabeth R, Weissman, Jonathan S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840789/
https://www.ncbi.nlm.nih.gov/pubmed/24302569
http://dx.doi.org/10.7554/eLife.01179