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Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster
Ribosomes can read through stop codons in a regulated manner, elongating rather than terminating the nascent peptide. Stop codon readthrough is essential to diverse viruses, and phylogenetically predicted to occur in a few hundred genes in Drosophila melanogaster, but the importance of regulated rea...
Autores principales: | Dunn, Joshua G, Foo, Catherine K, Belletier, Nicolette G, Gavis, Elizabeth R, Weissman, Jonathan S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840789/ https://www.ncbi.nlm.nih.gov/pubmed/24302569 http://dx.doi.org/10.7554/eLife.01179 |
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