Molecular interactions involved in proton-dependent gating in KcsA potassium channels

The bacterial potassium channel KcsA is gated open by the binding of protons to amino acids on the intracellular side of the channel. We have identified, via channel mutagenesis and x-ray crystallography, two pH-sensing amino acids and a set of nearby residues involved in molecular interactions that...

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Detalles Bibliográficos
Autores principales: Posson, David J., Thompson, Ameer N., McCoy, Jason G., Nimigean, Crina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840921/
https://www.ncbi.nlm.nih.gov/pubmed/24218397
http://dx.doi.org/10.1085/jgp.201311057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840921/
https://www.ncbi.nlm.nih.gov/pubmed/24218397
http://dx.doi.org/10.1085/jgp.201311057

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