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Pericellular Ca(2+) recycling potentiates thrombin-evoked Ca(2+) signals in human platelets

We have previously demonstrated that Na(+)/Ca(2+) exchangers (NCXs) potentiate Ca(2+) signaling evoked by thapsigargin in human platelets, via their ability to modulate the secretion of autocoids from dense granules. This link was confirmed in platelets stimulated with the physiological agonist, thr...

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Detalles Bibliográficos
Autores principales: Sage, Stewart O, Pugh, Nicholas, Farndale, Richard W, Harper, Alan G S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841026/
https://www.ncbi.nlm.nih.gov/pubmed/24303163
http://dx.doi.org/10.1002/phy2.85