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Oxyntomodulin increases intrinsic heart rate through the glucagon receptor

Two hormones from the gastrointestinal tract, glucagon and oxyntomodulin (OXM), vigorously elevate the intrinsic heart rate (I(HR)) of mice. We have previously shown that OXM influences murine heart rate (HR) independent of the glucagon-like peptide 1 (GLP-1) receptor. Here, we demonstrate using rad...

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Detalles Bibliográficos
Autores principales: Mukharji, Auyon, Drucker, Daniel J, Charron, Maureen J, Swoap, Steven J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841047/
https://www.ncbi.nlm.nih.gov/pubmed/24303183
http://dx.doi.org/10.1002/phy2.112