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Analyses of the effects of Gq protein on the activated states of the muscarinic M(3) receptor and the purinergic P2Y(1) receptor

G protein–coupled receptors (GPCRs) cause various cellular responses through activating heterotrimeric G protein upon the agonist binding. The interaction with G protein has been suggested to stabilize the agonist-bound active conformation of GPCRs. We previously reported the effects of Gq protein o...

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Detalles Bibliográficos
Autores principales: Tateyama, Michihiro, Kubo, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841061/
https://www.ncbi.nlm.nih.gov/pubmed/24303197
http://dx.doi.org/10.1002/phy2.134