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Inhibition of Elongation Factor-2 Kinase Augments the Antitumor Activity of Temozolomide against Glioma

BACKGROUND: Glioblastoma multiforme (GBM), the most common form of brain cancer with an average survival of less than 12 months, is a highly aggressive and fatal disease characterized by survival of glioma cells following initial treatment, invasion through the brain parenchyma and destruction of no...

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Detalles Bibliográficos
Autores principales: Liu, Xiao-yuan, Zhang, Li, Wu, JianPing, Zhou, Lei, Ren, Yi-Jie, Yang, Wei-Qiong, Ming, Zi-Jun, Chen, Bo, Wang, Jianrong, Zhang, Yi, Yang, Jin-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841121/
https://www.ncbi.nlm.nih.gov/pubmed/24303044
http://dx.doi.org/10.1371/journal.pone.0081345