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Mice with Deficient BK Channel Function Show Impaired Prepulse Inhibition and Spatial Learning, but Normal Working and Spatial Reference Memory

Genetic variations in the large-conductance, voltage- and calcium activated potassium channels (BK channels) have been recently implicated in mental retardation, autism and schizophrenia which all come along with severe cognitive impairments. In the present study we investigate the effects of functi...

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Detalles Bibliográficos
Autores principales: Typlt, Marei, Mirkowski, Magdalena, Azzopardi, Erin, Ruettiger, Lukas, Ruth, Peter, Schmid, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841135/
https://www.ncbi.nlm.nih.gov/pubmed/24303038
http://dx.doi.org/10.1371/journal.pone.0081270