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Early Deficits in Glycolysis Are Specific to Striatal Neurons from a Rat Model of Huntington Disease

In Huntington disease (HD), there is increasing evidence for a link between mutant huntingtin expression, mitochondrial dysfunction, energetic deficits and neurodegeneration but the precise nature, causes and order of these events remain to be determined. In this work, our objective was to evaluate...

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Detalles Bibliográficos
Autores principales: Gouarné, Caroline, Tardif, Gwenaëlle, Tracz, Jennifer, Latyszenok, Virginie, Michaud, Magali, Clemens, Laura Emily, Yu-Taeger, Libo, Nguyen, Huu Phuc, Bordet, Thierry, Pruss, Rebecca M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841140/
https://www.ncbi.nlm.nih.gov/pubmed/24303051
http://dx.doi.org/10.1371/journal.pone.0081528