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Early Deficits in Glycolysis Are Specific to Striatal Neurons from a Rat Model of Huntington Disease
In Huntington disease (HD), there is increasing evidence for a link between mutant huntingtin expression, mitochondrial dysfunction, energetic deficits and neurodegeneration but the precise nature, causes and order of these events remain to be determined. In this work, our objective was to evaluate...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841140/ https://www.ncbi.nlm.nih.gov/pubmed/24303051 http://dx.doi.org/10.1371/journal.pone.0081528 |