Galectin-3 Silencing Inhibits Epirubicin-Induced ATP Binding Cassette Transporters and Activates the Mitochondrial Apoptosis Pathway via β-Catenin/GSK-3β Modulation in Colorectal Carcinoma

Multidrug resistance (MDR), an unfavorable factor compromising the treatment efficacy of anticancer drugs, involves the upregulation of ATP binding cassette (ABC) transporters and induction of galectin-3 signaling. Galectin-3 plays an anti-apoptotic role in many cancer cells and regulates various pa...

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Detalles Bibliográficos
Autores principales: Lee, Yung-Kuo, Lin, Tsung-Hsien, Chang, Chuan-Fa, Lo, Yu-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841143/
https://www.ncbi.nlm.nih.gov/pubmed/24303084
http://dx.doi.org/10.1371/journal.pone.0082478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841143/
https://www.ncbi.nlm.nih.gov/pubmed/24303084
http://dx.doi.org/10.1371/journal.pone.0082478

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