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Gene Expression Signature of Normal Cell-of-Origin Predicts Ovarian Tumor Outcomes

The potential role of the cell-of-origin in determining the tumor phenotype has been raised, but not adequately examined. We hypothesized that distinct cells-of-origin may play a role in determining ovarian tumor phenotype and outcome. Here we describe a new cell culture medium for in vitro culture...

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Detalles Bibliográficos
Autores principales: Merritt, Melissa A., Bentink, Stefan, Schwede, Matthew, Iwanicki, Marcin P., Quackenbush, John, Woo, Terri, Agoston, Elin S., Reinhardt, Ferenc, Crum, Christopher P., Berkowitz, Ross S., Mok, Samuel C., Witt, Abigail E., Jones, Michelle A., Wang, Bin, Ince, Tan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841174/
https://www.ncbi.nlm.nih.gov/pubmed/24303006
http://dx.doi.org/10.1371/journal.pone.0080314