The Influence of N-Linked Glycans on the Molecular Dynamics of the HIV-1 gp120 V3 Loop

N-linked glycans attached to specific amino acids of the gp120 envelope trimer of a HIV virion can modulate the binding affinity of gp120 to CD4, influence coreceptor tropism, and play an important role in neutralising antibody responses. Because of the challenges associated with crystallising fully...

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Detalles Bibliográficos
Autores principales: Wood, Natasha T., Fadda, Elisa, Davis, Robert, Grant, Oliver C., Martin, Joanne C., Woods, Robert J., Travers, Simon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841175/
https://www.ncbi.nlm.nih.gov/pubmed/24303005
http://dx.doi.org/10.1371/journal.pone.0080301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841175/
https://www.ncbi.nlm.nih.gov/pubmed/24303005
http://dx.doi.org/10.1371/journal.pone.0080301

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