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In Vivo Regulation of Brain-Derived Neurotrophic Factor in Dorsal Root Ganglia Is Mediated by Nerve Growth Factor-Triggered Akt Activation during Cystitis

The role of brain-derived neurotrophic factor (BDNF) in sensory hypersensitivity has been suggested; however the molecular mechanisms and signal transduction that regulate BDNF expression in primary afferent neurons during visceral inflammation are not clear. Here we used a rat model of cystitis and...

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Detalles Bibliográficos
Autores principales: Qiao, Li-Ya, Yu, Sharon J., Kay, Jarren C., Xia, Chun-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841217/
https://www.ncbi.nlm.nih.gov/pubmed/24303055
http://dx.doi.org/10.1371/journal.pone.0081547