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miR-146a Enhances the Oncogenicity of Oral Carcinoma by Concomitant Targeting of the IRAK1, TRAF6 and NUMB Genes

MicroRNAs are short non-coding RNAs that regulate gene expression and are crucial to tumorigenesis. Oral squamous cell carcinoma (OSCC) is a prevalent malignancy worldwide. Up-regulation of miR-146 has been identified in OSCC tissues. However, the roles of miR-146 in carcinogenesis are controversial...

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Detalles Bibliográficos
Autores principales: Hung, Pei-Shi, Liu, Chung-Ji, Chou, Chung-Shan, Kao, Shou-Yen, Yang, Cheng-Chieh, Chang, Kuo-Wei, Chiu, Ting-Hui, Lin, Shu-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841223/
https://www.ncbi.nlm.nih.gov/pubmed/24302991
http://dx.doi.org/10.1371/journal.pone.0079926