Cargando…

The CCR4 Deadenylase Acts with Nanos and Pumilio in the Fine-Tuning of Mei-P26 Expression to Promote Germline Stem Cell Self-Renewal

Translational regulation plays an essential role in Drosophila ovarian germline stem cell (GSC) biology. GSC self-renewal requires two translational repressors, Nanos (Nos) and Pumilio (Pum), which repress the expression of differentiation factors in the stem cells. The molecular mechanisms underlyi...

Descripción completa

Detalles Bibliográficos
Autores principales: Joly, Willy, Chartier, Aymeric, Rojas-Rios, Patricia, Busseau, Isabelle, Simonelig, Martine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841267/
https://www.ncbi.nlm.nih.gov/pubmed/24286029
http://dx.doi.org/10.1016/j.stemcr.2013.09.007