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The neuroprotective effect of immune serum of adeno-associated virus vaccine containing Aβ1-15 gene on amyloid toxicity

OBJECTIVE: The aim of this study was to explore the effect of adeno-associated virus (AAV) serotype 2 vector vaccine containing amyloid-β peptide (Aβ) 1-15 gene fragment (AAV-Aβ15) immunized mice sera on counteracting Aβ1-42 peptide toxicity towards a primary culture cortical neurons. MATERIALS AND...

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Detalles Bibliográficos
Autores principales: Liu, Ling-Yun, Ma, Yuan-Yuan, Yang, Tao, Li, Xin, Li, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841610/
https://www.ncbi.nlm.nih.gov/pubmed/24339589
http://dx.doi.org/10.4103/0972-2327.120489