Computational Prediction of Drug Solubility in Lipid Based Formulation Excipients

PURPOSE: To investigate if drug solubility in pharmaceutical excipients used in lipid based formulations (LBFs) can be predicted from physicochemical properties. METHODS: Solubility was measured for 30 structurally diverse drug molecules in soybean oil (SBO, long-chain triglyceride; TG(LC)), Captex3...

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Detalles Bibliográficos
Autores principales: Persson, Linda C., Porter, Christopher J. H., Charman, William N., Bergström, Christel A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841656/
https://www.ncbi.nlm.nih.gov/pubmed/23771564
http://dx.doi.org/10.1007/s11095-013-1083-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841656/
https://www.ncbi.nlm.nih.gov/pubmed/23771564
http://dx.doi.org/10.1007/s11095-013-1083-7

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