A p53 enhancer region regulates target genes through chromatin conformations in cis and in trans

We examined how a p53 enhancer transmits regulatory information in vivo. Using genetic ablation together with digital chromosome conformation capture and fluorescent in situ hybridization, we found that a Drosophila p53 enhancer region (referred to as the p53 response element [p53RE]) physically con...

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Detalles Bibliográficos
Autores principales: Link, Nichole, Kurtz, Paula, O'Neal, Melissa, Garcia-Hughes, Gianella, Abrams, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841732/
https://www.ncbi.nlm.nih.gov/pubmed/24240233
http://dx.doi.org/10.1101/gad.225565.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841732/
https://www.ncbi.nlm.nih.gov/pubmed/24240233
http://dx.doi.org/10.1101/gad.225565.113

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