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A p53 enhancer region regulates target genes through chromatin conformations in cis and in trans

We examined how a p53 enhancer transmits regulatory information in vivo. Using genetic ablation together with digital chromosome conformation capture and fluorescent in situ hybridization, we found that a Drosophila p53 enhancer region (referred to as the p53 response element [p53RE]) physically con...

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Detalles Bibliográficos
Autores principales:	Link, Nichole, Kurtz, Paula, O'Neal, Melissa, Garcia-Hughes, Gianella, Abrams, John M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2013
Materias:	Research Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841732/ https://www.ncbi.nlm.nih.gov/pubmed/24240233 http://dx.doi.org/10.1101/gad.225565.113

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