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In the Crosshairs: Investigating Lytic Granules by High-Resolution Microscopy and Electrophysiology
Cytotoxic T lymphocytes (CTLs) form an integral part of the adaptive immune system. Their main function is to eliminate bacteria- and virus-infected target cells by releasing perforin and granzymes (the lethal hit) contained within lytic granules (LGs), at the CTL-target-cell interface [the immunolo...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841761/ https://www.ncbi.nlm.nih.gov/pubmed/24348478 http://dx.doi.org/10.3389/fimmu.2013.00411 |