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In the Crosshairs: Investigating Lytic Granules by High-Resolution Microscopy and Electrophysiology

Cytotoxic T lymphocytes (CTLs) form an integral part of the adaptive immune system. Their main function is to eliminate bacteria- and virus-infected target cells by releasing perforin and granzymes (the lethal hit) contained within lytic granules (LGs), at the CTL-target-cell interface [the immunolo...

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Detalles Bibliográficos
Autores principales:	Pattu, Varsha, Halimani, Mahantappa, Ming, Min, Schirra, Claudia, Hahn, Ulrike, Bzeih, Hawraa, Chang, Hsin-Fang, Weins, Lisa, Krause, Elmar, Rettig, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841761/ https://www.ncbi.nlm.nih.gov/pubmed/24348478 http://dx.doi.org/10.3389/fimmu.2013.00411

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