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Indomethacin-Enhanced Anticancer Effect of Arsenic Trioxide in A549 Cell Line: Involvement of Apoptosis and Phospho-ERK and p38 MAPK Pathways

Background. Focusing on novel drug combinations that target different pathways especially apoptosis and MAPK could be a rationale for combination therapy in successful treatment of lung cancer. Concurrent use of cyclooxygenase (COX) inhibitors with arsenic trioxide (ATO) might be a possible treatmen...

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Detalles Bibliográficos
Autores principales: Mandegary, Ali, Torshabi, Maryam, Seyedabadi, Mohammad, Amirheidari, Bagher, Sharif, Elham, Ghahremani, Mohammad Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842073/
https://www.ncbi.nlm.nih.gov/pubmed/24312908
http://dx.doi.org/10.1155/2013/237543